New York City Mayor Eric Adams has been indicted on criminal charges in federal court in Manhattan, sources familiar with the matter told CNBC on Wednesday night.

The indictment, which remains sealed for now, at least in part accuses Adams of criminal conduct related to donations to his 2021 mayoral campaign.

A source said that the indictment mentions up to $20 million in donations that Adams’ campaign received as a result of matching fund program that the city’s Campaign Finance Program offers candidates for small-dollar donations made to them by residents of New York City.

Adams, a former police captain, is at least the second New York mayor to be criminally charged while still in office, and is the first official in his administration to be charged as a result of multiple pending investigations that have ensnared the New York Police Department and the city’s top schools’ official.

It was previously known the Manhattan U.S. Attorney’s Office was investigating Adams for potentially conspiring with the government of Turkey to funnel illegal donations into that campaign.

The New York Times on Monday reported that prosecutors had submitted grand jury subpoenas to City Hall, Adams, and his campaign in July demanding information related to four other countries: Israel, China, Qatar, South Korea, and Uzbekistan.

Adams issued a defiant statement Wednesday night after news of the indictment broke.

“I always knew that If I stood my ground for New Yorkers that I would be a target — and a target I became,” he said.

“If I am charged, I am innocent and I will fight this with every ounce of my strength and spirit,” said Adams, who after working in the Police Department served as a state senator and Brooklyn Borough President.

The U.S. Attorney’s Office and the FBI declined to comment on the indictment.

Earlier Wednesday, Rep. Alexandria Ocasio-Cortez, D-N.Y., called on the mayor to resign, saying the “flood of resignations and vacancies” resulting from various federal probes of administration officials “are threatening government functions.”

“For the good of the city he should resign,” Ocasio-Cortez said.

If Adams resigns before his first term in office ends, he would be replaced by New York City Public Advocate Jumaane Williams as acting mayor.

There are multiple federal investigations into Adams and people affiliated with him and his administration.

On Tuesday, city Schools Chancellor David Banks told Adams he expected to retire at the end of 2024.

Banks’ surprise announcement came weeks after federal authorities seized electronic devices belonging to him, his brother, Deputy Mayor Phil Banks, and his fiancee, Deputy Mayor Sheena Wright.

Another Banks brother, Terence, is being investigated by the Manhattan U.S. Attorney’s Office in connection with the allocation of city contacts worth millions of dollars to the companies who received them after hiring Terence Banks’ consulting firm.

The same federal prosecutors’ office is investigating whether James Caban, the twin brother of former New York Police Commissioner Edward Caban, exploited his ties to his brother and the NYPD to benefit his nightclub security business.

Edward Caban resigned as police commissioner on Sept. 12, a week after his own phone was seized by federal investigators.

Three days after Edward Caban resigned, Adam’s mayoral counsel and chief legal advisor Lisa Zornberg resigned, saying she had “concluded that I can no longer serve in my position.”

Last Friday, federal investigators executed search warrants at the homes of Thomas Donlon, the acting NYPD commissioner.

Donlon, who is a former top FBI counterterrorism official in New York, said this week that the investigators “took materials that came into my possession approximately 20 years ago and are unrelated to my work with the New York City Police Department.”

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